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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
13.33
Human Site:
S631
Identified Species:
22.56
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S631
G
T
L
S
V
R
V
S
P
P
Q
P
I
L
S
Chimpanzee
Pan troglodytes
XP_509441
819
90122
P601
Q
S
P
S
P
Q
S
P
Q
N
N
C
S
G
K
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
K194
Y
Y
K
K
R
L
R
K
S
S
R
E
E
D
L
Dog
Lupus familis
XP_546925
857
93734
S636
G
T
L
S
V
H
V
S
P
P
Q
P
I
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
S643
G
A
L
S
V
H
L
S
P
P
Q
T
V
L
S
Rat
Rattus norvegicus
Q6AXT8
471
49872
P275
G
P
A
P
S
G
P
P
G
P
P
Q
M
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
S675
P
P
P
G
T
T
I
S
L
H
H
P
P
S
R
Frog
Xenopus laevis
NP_001084764
548
60887
L352
P
V
N
L
D
E
E
L
I
P
S
P
G
P
P
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
P606
G
V
E
Q
V
P
S
P
Q
S
P
L
S
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
Q610
E
S
T
F
H
E
S
Q
D
S
P
L
S
P
T
Honey Bee
Apis mellifera
XP_394429
1014
115124
S792
M
S
I
G
S
P
L
S
P
N
R
G
Y
I
K
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
S693
I
L
E
S
P
S
T
S
G
D
I
S
G
P
A
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
T1093
P
P
T
A
G
F
F
T
S
S
L
A
S
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
S863
W
A
E
T
Q
M
S
S
E
A
S
K
A
P
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
6.6
0
93.3
N.A.
66.6
13.3
N.A.
N.A.
13.3
13.3
20
N.A.
0
13.3
13.3
0
P-Site Similarity:
100
20
6.6
93.3
N.A.
80
20
N.A.
N.A.
20
13.3
20
N.A.
13.3
46.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
8
0
0
0
0
0
8
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
8
8
0
0
0
8
8
% D
% Glu:
8
0
22
0
0
15
8
0
8
0
0
8
8
0
0
% E
% Phe:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
8
% F
% Gly:
36
0
0
15
8
8
0
0
15
0
0
8
15
8
0
% G
% His:
0
0
0
0
8
15
0
0
0
8
8
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
8
0
8
0
8
0
15
8
0
% I
% Lys:
0
0
8
8
0
0
0
8
0
0
0
8
0
0
15
% K
% Leu:
0
8
22
8
0
8
15
8
8
0
8
15
0
22
8
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
15
8
0
0
0
0
% N
% Pro:
22
22
15
8
15
15
8
22
29
36
22
29
8
36
15
% P
% Gln:
8
0
0
8
8
8
0
8
15
0
22
8
0
0
0
% Q
% Arg:
0
0
0
0
8
8
8
0
0
0
15
0
0
0
8
% R
% Ser:
0
22
0
36
15
8
29
50
15
29
15
8
29
8
29
% S
% Thr:
0
15
15
8
8
8
8
8
0
0
0
8
0
8
8
% T
% Val:
0
15
0
0
29
0
15
0
0
0
0
0
8
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _